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Viral reservoir as obstacle to cure
Chairs: F. Bai (Milano), C. Pinnetti (Roma), F. Saladini (Siena)
The persistence of the viral reservoir is still the main obstacle to the eradication of HIV infection. The availability of new high-sensitivity techniques of investigation has allowed to increase the ability to characterize the reservoir, but leaving open questions about the reliability of the methods and the clinical significance of generated data. The course aims to present the current status of technologies potential aimed at the qualitative and quantitative assessment of reservoir in the patient follow-up, and deepen the current therapeutic strategies to limit the extent of viral reservoir as the first approach to HIV cure. Attendees will be involved with a questionnaire to evaluate the perception of the usefulness of some diagnostic tests or clinical markers for the patient's routine follow-up. The results of the survey will be discussed at the end of the course.
|13.30 - 14.00||Measuring the reservoir today||Maria Santoro, Roma|
|14.00 - 14.30||Evolution of reservoir during the infection: immunological aspects||Alessandra Bandera, Milano|
|14.30 - 15.00||Evolution of reservoir during the infection: virological aspects||Francesca Ceccherini-Silberstein, Roma|
|15.00 - 15.30||Antiretrovirals distribution in sanctuaries||Andrea Calcagno, Torino|
|15.30 - 16.00||Discussion of survey results and conclusions|
Ageing with HIV infection: new scenarios and new challenges
Chairs: A. Mondi (Roma), V. Spagnuolo (Milano)
By 2030, 70% of HIV-infected patients will be 50 years of age or older and one third of people living with HIV will have at least three age-related comorbidities.
In light of this changing epidemiology, HIV providers must recognize and manage this new picture of the disease. In addition to multiple comorbidities, the ageing HIV population is at risk for geriatric syndromes, such as frailty, falls, delirium and functional impairment.
It is therefore necessary to adopt a multidisciplinary approach to the patient and a proactive management of comorbidities. Nevertheless, in the elderly subject with HIV infection, the personalization of antiretroviral therapy, which must be based on an in-depth knowledge of the characteristics of antiretroviral drugs, drug interactions with concomitant therapy and patient's clinical characteristics, is even more important.
|13.30 - 14.00||Ageing with HIV: current and future dimensions of an epidemic||Giordano Madeddu, Sassari|
|14.00 - 14.30||Immunosenescence and inflammaging: from basic research to clinic||Gabriella d’Ettorre, Roma|
|14.30 - 15.00||Diagnosis and screening of frailty in ageing with HIV Infection||Giovanni Guaraldi, Modena|
|15.00 - 15.30||Diagnosis and screening of neurocognitive disease in HIV||Paola Maria Cinque, Milano|
|15.30 - 16.00||Managing polypharmacy in elderly patient||Cristina Gervasoni, Milano|
Prevention and treatment of sexually transmitted diseases (STDs)
Chairs: A. Muscatello (Milano), S. Nozza (Milano), R. Rossotti (Milano)
Sexually transmitted diseases (STDs) are infections that are passed from one person to another through sexual contact. Antibiotics can treat STDs caused by bacteria, yeast, or parasites; for this correct diagnosis and treatment are crucial.
PrEP (pre-exposure prophylaxis) has been shown to reduce the risk of HIV infection in people who are at high risk by up to 92% when taken consistently. Italian regulatory agency approved use of PrEP.
This course is focused on STDs diagnosis and treatment and on PrEP request and management in clinical practice.
|13.30 - 13.50||The current management of sexually transmitted diseases||Marco Cusini, Milano|
|13.50 - 14.10||The support of the laboratory in STDs early diagnosis||Maria Agnese Latino, Torino|
|14.10 - 14.30||Indications and clinical implications of vaccinations against STDs||Maurizio Orso, Milano|
|14.30 - 14.45||The role of counselor and cultural mediator in prevention||Giorgia Fracca, Milano|
|14.45 - 15.00||The PrEP clinic in hospital||Rita Bellagamba, Roma|
|15.00 - 15.15||The PrEP clinic in check points||Lorenzo Badia, Bologna|
|15.15 - 16.00||Discussion|
HIV and chronic viral hepatitis: the strategic role of the nurse
Chairs: A. Bigoloni (Milano), V. Picciotto (Milano)
The current management of HIV-HCV co-infected patient in the clinic today requires more than ever, due to the characteristics of complexity, a management based on close medical-nurse collaboration and team-based approach to the patient.
We will therefore define the role of the nurse in relation to the patient's helping relationship with new disease response and support for adherence to therapy, knowledge of HIV and HCV drugs and the role of the nurse in clinical research.
|13.30 - 14.00||Communication of diagnosis and management of disease chronicity: the point of view of the patient and the operator||Claudio Ruggieri, Milano|
|14.00 - 14.30||New anti-HIV and HCV drugs: interactions and undesirable effects||Teresa Angelini Zucchetti, Milano|
|14.30 - 15.00||Health counseling and adherence to therapy||Viviana Picciotto, Milano|
|15.00 - 15.30||Role of the nurse in clinical trial||Duilio F. Manara, Milano|
|15.30 - 16.00||Discussion|